The Evolution of Two-Component Systems in Bacteria Reveals Different Strategies for Niche Adaptation
Figure 10
Genomic Distribution of HPKs and RRs
The position of signaling proteins in several genomes is shown. In the outer ring, HPKs of different classes are shown: Old (gray), LSE (purple), HGT without duplication (blue), and genes that recently underwent a “Birth” event (green). The middle ring shows the position of response regulators, with blue colors indicating hybrid response regulators (containing HPK domains). The inner ring shows the location of all genes in each genome annotated as signaling proteins according to the MicrobesOnline database [37].