Phylogenetic Reconstruction of Orthology, Paralogy, and Conserved Synteny for Dog and Human
Figure 9
Venn Diagram Comparing Orthology Relationships Predicted by PhyOP, Ensembl, and Inparanoid
(A) Most 1:1 orthologue predictions are shared between the three methods: PhyOP (solid rectangle), Ensembl (striped rectangle), and Inparanoid (hollow rectangle).
(B) Orthology predictions that involve lineage-specific duplications, however, differ markedly between PhyOP and Ensembl. Most Inparanoid predictions are a subset of those from Ensembl.
(C) The same is true for predicted paralogy relationships.