Model-Based Design of Growth-Attenuated Viruses
Figure 8
Predicted Levels of Virion Production and G Protein Expression in BHK Cells Infected with VSV Strains (Total 20 Strains)
(A) Virion production.
(B) G protein expression.
The size of each circle shows the relative level for each VSV strain, and the coordinate of each circle indicates the gene order in each strain's genome. The gray and white circles denote the cases of wild-type (N1G4) and non–wild-type strains, respectively. Under the line there is no VSV strain case (e.g., N1G1, N2G2, etc.). Vex(0) = 3.