Evidence of Influence of Genomic DNA Sequence on Human X Chromosome Inactivation
Figure 2
Boxplots Representing the Content of Alu, L1, L2, MIR, and ACG/CGT 3-mers in 100-kb Windows Surrounding the Transcription Starts of Genes
For each boxplot, horizontal lines indicate the locations of the lower quartile, median, and upper quartile values. Notches represent a robust estimate of the uncertainty about the medians for box-to-box comparison. Boxes whose notches do not overlap indicate that the medians of the two groups differ at the 0.05 significance level. Clear boxes represent genes that escape inactivation, while shaded boxes represent genes subject to inactivation [12]. Analyses were done with all genes for which X inactivation status is known (n = 448) or with genes from the XAR region (n = 110). y-Axes in all plots represent the average content of each sequence feature in 100-kb windows surrounding the transcription starts of genes.