Single-Molecule Dynamics Reveals Cooperative Binding-Folding in Protein Recognition
Figure 8
Typical Structures and their Corresponding Configuration in the Free-Energy Landscape
Typical structures of loosely bound state (left structure), transition state (middle structure), and bound state (right structure) and their corresponding configuration in free-energy profiles in terms of fraction of native (interface) contacts between Cdc42 and CBD portion of WASP, as well as the fraction of native (folding) contacts of CBD itself.