A Community Resource Benchmarking Predictions of Peptide Binding to MHC-I Molecules
Figure 5
Scheme to Integrate Prediction Methods
Shown is a prediction framework providing a common interface to different prediction methods to generate new tools and retrieve predictions from them. A prediction method has to accept a set of peptides with measured affinities with which it can train a new prediction tool. It returns the URI of the new tool to the evaluation server. Using the URI, the evaluation server can check for the state of the new tool to see if training is still ongoing or if an error occurred during training. Once the tool training is completed, it has to accept a set of peptide sequences and return predicted affinities for them. The format for the data exchanged in each of these steps is defined in an xml schema definition (.xsd file), available at http://mhcbindingpredictions.immuneepitope.org.