Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays
Figure 6
Inferred LOH in Prostate Cancer Samples Identifies Regions of LOH Known to Be Frequent in Prostate Cancer
The mean LOH probability across 34 prostate cancer samples is plotted along the left for all chromosomes. Peak regions of LOH are noted, and data from Chromosomes 8, 13, and 17 are highlighted on the right. These data are displayed as in Figure 3. Note that in this view, SNPs are visualized proportionally to physical distance along the chromosome, and most SNPs are not projected due to proximity to their neighbors. The red dotted lines indicate the approximate chromosomal positions of putative TSGs.