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Identification and Classification of Conserved RNA Secondary Structures in the Human Genome

Figure 6

Clover-Shaped Fold Predictions

(A) Gene structure, EvoFold predictions, and cDNAs around the end of the gene ZNF207. The 3′UTR and the intron of an alternative splice variant harbor high-scoring clover-shaped fold predictions.

(B) Annotated segment of eight-way alignment spanning the 3′UTR fold (see Figure 3B for legend).

(C) Depictions of 3′UTR fold (left) and intronic fold (right).

(D) Annotated alignment of human primary sequences of 3′UTR and intronic folds. The alignment is annotated with the secondary structures of the folds and substitution differences in corresponding pairs are color-coded (see Figure 3B for color legend).

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.0020033.g006