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Conformational Changes in Protein Loops and Helices Induced by Post-Translational Phosphorylation

Figure 4

Detailed View of One Portion of the Structural Superposition between the Phosphorylated and Unphosphorylated Crystal Structures of CDK2/Cyclin A

The phosphorylated activation loop (blue) passes through the middle of Tyr179 (CPK) when inserted into the non-phosphorylated structure (green) of CDK2. Figure prepared with Chimera [72].

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.0020032.g004