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Role of Mechanical Factors in the Morphology of the Primate Cerebral Cortex

Figure 7

Effect of Cortical Folding on Neuron Number

Number of neurons found below a unit of 1 mm2 surface area and extending to the variable width of the upper (II+III+IV) and deep (V+VI) layers of gyral, intermediate, and sulcal cortices. Layer I was excluded from the analyses because of its separate developmental path and paucity of neurons [31]. There were significantly fewer neurons in layers V+VI of intermediate areas than in gyral areas and in the deep layers of sulcal than intermediate areas (pairwise t tests, Bonferroni-adjusted, p < 0.05). Conversely, there were more neurons in the upper layers of sulcal areas than in intermediate or gyral areas.

Figure 7

doi: https://doi.org/10.1371/journal.pcbi.0020022.g007