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Role of Mechanical Factors in the Morphology of the Primate Cerebral Cortex

Figure 6

Effect of Cortical Folding on Absolute and Relative Thickness of Cortical Layers

Coronal section through medial prefrontal cortex of a rhesus monkey brain in the anterior cingulate. Note the expanded deep layers (below dotted line demarcating the upper boundary of cortical layer V) in the gyral regions (large arrows), contrasted by reduced thickness of the deep layers at the bottom of the cingulate sulcus (arrowhead) and the expanded layer I (small arrow) in comparison with layer I in gyral cortex. The brain section was immunoreacted for NeuN, a neuronal marker (brown), and then stained for Nissl (blue).

Figure 6

doi: https://doi.org/10.1371/journal.pcbi.0020022.g006