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The Fragile Breakage versus Random Breakage Models of Chromosome Evolution

Figure 4

GRIMM-Synteny and ST-Synteny on the Same Simulated Data

The genomic dot-plot is shown in thick green. The synteny blocks identified by GRIMM-Synteny are shown as blue rectangles, and the ones from ST-Synteny are dashed red rectangles. When block coordinates coincide, this appears as dashed blue/red. Signs of the blocks are shown as diagonals. Tiny blocks have been artificially enlarged for visibility and do not actually protrude into other blocks. The simulated human genome has anchors 1 through 5,000. The simulated mouse genome was generated as π = Simulation(5000, 15, 500, 5). Blocks were identified via GRIMM-Synteny(π, 8, 3) and ST-Synteny(π, 5, 3).

Figure 4

doi: https://doi.org/10.1371/journal.pcbi.0020014.g004