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The Fragile Breakage versus Random Breakage Models of Chromosome Evolution

Figure 2

Asymmetric Treatment of Genomes by ST-Synteny

In comparing two genomes, ST-Synteny may produce different synteny blocks depending on which one is chosen as the reference genome. The synteny blocks produced by ST-Synteny are shown as red boxes around the anchors.

(A) The genome shown on the y-axis is the reference genome 1, …, 10, and the genome shown on the x-axis is represented as a permutation π of this.

(B) The exact same anchor arrangement is shown, but the x-axis is taken as the reference genome 1, …, 10 and the y-axis is the permutation π−1. Although the anchor arrangements are identical, ST-Synteny with parameters w = 2, Δ = 1 produces different blocks depending on which genome is the reference genome.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.0020014.g002