Dependency Map of Proteins in the Small Ribosomal Subunit
Figure 2
The Influence Network of the Presence of Single Proteins on the Binding Stability of the Other Proteins
The three clusters and the four unaffected proteins are visible. The colors of the arrows indicate Δr (the larger the number, the stronger the influence). The arrows point from the removed protein to the affected protein, e.g., removal of S4 alters the binding strength of S5 with the “influence strength” of 3. The gray arrows indicate the interaction that is due to very small relative energy change and involves the “suspicious” protein S12 (see text for details).