Unusual Intron Conservation near Tissue-Regulated Exons Found by Splicing Microarrays
Figure 6
Multiple Alignment of the Flanking Intron Sequences Downstream of the Alternative Exons from Baiap1 (MAGI-1), Acvrinp1 (MAGI-2), and 4732496O19Rik (MAGI-3) and the Orthologous Sequences from Rat, Human, Dog, and Chicken
While the orthologous sequences have high conservation between them (A), the paralogous sequences have diverged considerably (B). The 5′ splice sites are at the left. Genome sequences similar to TACTAAC are between gray bars. In the region downstream of the 5′ splice site these may act as regulatory binding sites for SF1, quaking (QK), or some other factor. Fox-1 sites are shown between black bars.