Refining Protein Subcellular Localization
Figure 3
Sub-Compartmental Prediction Scheme
Proteins are predicted to be localized in one specific sub-compartment by first considering the most likely PSLT2 compartment (blue boxes). Further decisions depend on the PSLT2 second most likely compartment prediction (orange boxes) and targeting information (green boxes). Once all information has been analyzed, the protein is predicted to be in one of 18 sub-compartments (pink boxes). When the second most likely sub-compartments are considered, the default prediction is shown with a star (this branch of the tree is used in particular when proteins have no second most likely compartment as predicted by PSLT2). Pero, peroxisome; Vac, vacuole; Cyt, cytosolic; memb, membrane; TMD, number of transmembrane domains in protein; ER, endoplasmic reticulum; GPI, presence of GPI anchor; Nuc, nuclear; PM, plasma membrane; Mito, mitochondria; S, signal peptide; A, signal anchor; Q, neither signal peptide nor signal anchor.