A Digital Atlas to Characterize the Mouse Brain Transcriptome
Figure 3
A Search for Genes that Are Expressed in the Substantia Nigra
(A) The pattern of Slc6a3 gene expression in and around the substantia nigra at standard section number 6 is set as the query pattern for a search of all 200 expression patterns in the current dataset. Note the color-coded shading of the query pattern, with red indicating the strong expression of Slc6a3 in the substantia nigra, and grey indicating no expression in the tissue surrounding the substantia nigra.
(B) The expression patterns in the substantia nigra pars compacta of the 12 genes found to match the search criterion best are shown: dopamine receptor 2 (Drd2); vesicular monoamine transporter 2 (Slc18a2); tyrosine hydroxylase (Th); alpha synuclein (Snca); a gene encoding a nuclear orphan receptor (Nr4a2); limb expression 1 homolog (Lix1); a gene encoding an aldehyde dehydrogenase (Aldh1a1); protein tyrosine phosphatase, receptor type L (Ptprl); chaperonin subunit 8 (Cct8); synaptic vesicle glycoprotein 2c (Sv2c); transmembrane protein 1 (Tmem1); and LIM homeobox transcription factor 1 beta (Lmx1b).