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Comparative Genomics and Disorder Prediction Identify Biologically Relevant SH3 Protein Interactions

Figure 2

Size of Probing Window When Looking for Conservation of the Consensus Sequence in Orthologs of the Putative Target Protein

We defined the conservation score as simply the number of species where the consensus sequence is conserved. With this information the accuracy and coverage were calculated, with the gold (A) and platinum (B) positive sets, for consensus sequence conserved in different numbers of species and for different sizes of the probing region.

Figure 2

doi: https://doi.org/10.1371/journal.pcbi.0010026.g002