The Genomic Pattern of tDNA Operon Expression in E. coli
Figure 5
Total Expression (Bulk Output) at μ = 2.5 Doublings/h of tDNA Operons Against Their Location in the E. coli K12 Genome
The angular scale is symbolized by α in the text, with 0° placed at the origin of replication (oriC) shown at the top. Units of the radial axis (expression) are initiations per min per picogram of culture mass. Leading strand operons are indicated in blue and lagging strand operons in gold. The red curve shows a re-estimated circular regression of all the data including only intercept and cosine terms, showing the significant tendency of expression to increase toward oriC, especially for leading strand operons. Values for lagging strand operons asnV, asnU, and asnT are covered but equal by constraint (see Table 2) to the value for asnW.