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Ten quick tips for causal analysis of biomedical omics data
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Gleb Svinin ,
Roles Writing – original draft, Writing – review & editing
¶☯ These authors contributed equally to this work and share first authorship.
Affiliation Biomedical Data Science Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg
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Rebecca Ting Jiin Loo ,
Roles Writing – original draft, Writing – review & editing
¶☯ These authors contributed equally to this work and share first authorship.
Affiliation Biomedical Data Science Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg
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Nikhilesh Vasantha Kumar ,
Roles Writing – original draft, Writing – review & editing
¶☯ These authors contributed equally to this work and share first authorship.
Affiliation Biomedical Data Science Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg
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Varsha Venkatesha Murthy ,
Roles Writing – original draft, Writing – review & editing
¶☯ These authors contributed equally to this work and share first authorship.
Affiliation Biomedical Data Science Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg
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Dilara Uzuner Odongo ,
Roles Writing – original draft, Writing – review & editing
¶☯ These authors contributed equally to this work and share first authorship.
Affiliation Biomedical Data Science Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg
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Ramón Díaz-Uriarte,
Roles Writing – review & editing
Affiliations Instituto de Investigaciones Biomédicas Sols-Morreale (IIBM), UAM-CSIC, Madrid, Spain, Department of Biochemistry, Universidad Autónoma de Madrid, Madrid, Spain
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Ana Conesa,
Roles Writing – review & editing
Affiliation Institute for Integrative Systems Biology, Spanish National Research Council, Valencia, Spain
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Gianluca Bontempi,
Roles Methodology, Writing – review & editing
Affiliation Machine Learning Group, Université Libre de Bruxelles, Bruxelles, Belgique and WEL Research Institute, Wavre, Belgique
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Susana Vinga,
Roles Writing – review & editing
Affiliation INESC-ID, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal
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Ilaria Granata,
Roles Writing – review & editing
Affiliation Institute for High Performance Computing and Networking, National Research Council, Naples, Italy
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Daniel Domingo-Fernández,
Roles Writing – review & editing
Affiliation Fraunhofer Institute for Algorithms and Scientific Computing, Sankt Augustin, Germany
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Paola Lecca,
Roles Writing – review & editing
Affiliation Faculty of Engineering, Free University of Bozen-Bolzano, Bolzano, Italy
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Marieke L. Kuijjer,
Roles Writing – review & editing
Affiliation Faculty of Medicine, University of Helsinki, Helsinki, Finland; Norwegian Centre for Molecular Biosciences and Medicine (NCMBM), University of Oslo, Oslo, Norway
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Jesse H. Krijthe,
Roles Writing – review & editing
Affiliation Pattern Recognition & Bioinformatics, Delft University of Technology, Delft, The Netherlands
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Ina Koch,
Roles Writing – review & editing
Affiliation Institute of Computer Science, Goethe University Frankfurt, Frankfurt, Germany
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Laurence Calzone,
Roles Writing – review & editing
Affiliation Institut Curie, Inserm U1331, PSL, Mines ParisTech, Paris, France
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Simona Ester Rombo,
Roles Writing – review & editing
Affiliation Department of Mathematics and Computer Science, University of Palermo, Palermo, Italy
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Fátima Sánchez-Cabo,
Roles Writing – review & editing
Affiliation Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain
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Enrico Glaab
Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: enrico.glaab@uni.lu
Affiliation Biomedical Data Science Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette, Luxembourg
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Ten quick tips for causal analysis of biomedical omics data
- Gleb Svinin,
- Rebecca Ting Jiin Loo,
- Nikhilesh Vasantha Kumar,
- Varsha Venkatesha Murthy,
- Dilara Uzuner Odongo,
- Ramón Díaz-Uriarte,
- Ana Conesa,
- Gianluca Bontempi,
- Susana Vinga,
- Ilaria Granata
- Published: August 20, 2026
- https://doi.org/10.1371/journal.pcbi.1014668