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Open Access
Peer-reviewed
Research Article
Quantification of beta-cell carrying capacity in prediabetes
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Aurore Woller ,
Contributed equally to this work with: Aurore Woller, Yuval Tamir
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing
Affiliations Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel, Unité de Chronobiologie théorique, Faculté des Sciences, Université Libre de Bruxelles (ULB), Brussels, Belgium
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Yuval Tamir ,
Contributed equally to this work with: Aurore Woller, Yuval Tamir
Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
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Alon Bar,
Roles Methodology, Validation, Writing – review & editing
Affiliation Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
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Avi Mayo,
Roles Formal analysis, Investigation, Methodology, Software, Visualization, Writing – review & editing
Affiliation Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
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Michal Rein,
Roles Data curation, Investigation, Writing – review & editing
Affiliations Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel, Department of Computer Sciences and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel
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Anastasia Godneva,
Roles Data curation, Methodology, Writing – review & editing
Affiliations Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel, Department of Computer Sciences and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel
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Netta Mendelson Cohen,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Computer Sciences and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel
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Eran Segal,
Roles Conceptualization, Data curation, Validation, Writing – review & editing
Affiliations Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel, Department of Computer Sciences and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel
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Yoel Toledano,
Roles Conceptualization, Writing – review & editing
Affiliation Division of Maternal Fetal Medicine, Helen Schneider Women’s Hospital, Rabin Medical Center, Petah Tikva, Israel
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Smadar Shilo,
Roles Data curation, Investigation, Writing – review & editing
Affiliations Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel, Department of Computer Sciences and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel, Jesse and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center, Petah Tikva, Israel, Faculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv, Israel
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Didier Gonze,
Roles Conceptualization, Supervision, Validation, Writing – review & editing
Affiliation Unité de Chronobiologie théorique, Faculté des Sciences, Université Libre de Bruxelles (ULB), Brussels, Belgium
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Uri Alon
Roles Conceptualization, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: uri.alon@weizmann.ac.il
Affiliation Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel
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Quantification of beta-cell carrying capacity in prediabetes
- Aurore Woller,
- Yuval Tamir,
- Alon Bar,
- Avi Mayo,
- Michal Rein,
- Anastasia Godneva,
- Netta Mendelson Cohen,
- Eran Segal,
- Yoel Toledano,
- Smadar Shilo
- Published: September 15, 2026
- https://doi.org/10.1371/journal.pcbi.1014589