TCRBinder: Unified pre-trained language model with paired-chain synergy for predicting T-cell receptor binding specificity

• Weihe Dong,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Writing – original draft

  Affiliation Faculty of Computing, Harbin Institute of Technology, Harbin, China

  https://orcid.org/0000-0001-8022-9793

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• Qiang Yang,

  Roles Formal analysis, Investigation, Validation

  Affiliations Faculty of Computing, Harbin Institute of Technology, Harbin, China, Zhengzhou Advanced Research Institute, Harbin Institute of Technology, Zhengzhou, China

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• Long Xu,

  Roles Data curation

  Affiliation Faculty of Computing, Harbin Institute of Technology, Harbin, China

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• Xiaokun Li ,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  * E-mail: 24B303024@stu.hit.edu.cn (XL); dongsuyu@126.com (SD); ghwang@hit.edu.cn (GW)

  Affiliations Faculty of Computing, Harbin Institute of Technology, Harbin, China, School of Computer and Big Data, Heilongjiang University, Harbin, China, Postdoctoral Program of Heilongjiang Hengxun Technology Co., Ltd., Harbin, China, Shandong Hengxun Technology Co., Ltd., Qingdao, China

  https://orcid.org/0000-0002-6645-6890

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• Kuanquan Wang,

  Roles Funding acquisition

  Affiliation Faculty of Computing, Harbin Institute of Technology, Harbin, China

  https://orcid.org/0000-0003-1347-3491

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• Suyu Dong ,

  Roles Formal analysis, Methodology, Supervision, Validation, Writing – original draft

  * E-mail: 24B303024@stu.hit.edu.cn (XL); dongsuyu@126.com (SD); ghwang@hit.edu.cn (GW)

  Affiliations Computer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia, Center of Excellence for Smart Health (KCSH), King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia, Center of Excellence on Generative AI, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia

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• Gongning Luo,

  Roles Funding acquisition

  Affiliation Faculty of Computing, Harbin Institute of Technology, Harbin, China

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• Xianyu Zhang,

  Roles Writing – review & editing

  Affiliation Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin, China

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• Tiansong Yang,

  Roles Writing – review & editing

  Affiliation Department of Rehabilitation, The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin, China

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• Xin Gao,

  Roles Project administration

  Affiliations Computer Science Program, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia, Center of Excellence for Smart Health (KCSH), King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia, Center of Excellence on Generative AI, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia

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• Guohua Wang

  Roles Investigation, Project administration, Supervision, Validation

  * E-mail: 24B303024@stu.hit.edu.cn (XL); dongsuyu@126.com (SD); ghwang@hit.edu.cn (GW)

  Affiliation Faculty of Computing, Harbin Institute of Technology, Harbin, China

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