A prototype-augmented graph representation learning framework for identifying brain disorder-associated genes and facilitating drug repurposing

• Jiafang Li ,

  Contributed equally to this work with: Jiafang Li, Yifei Li

  Roles Data curation, Investigation, Methodology, Software, Validation, Writing – original draft

  Affiliations Department of Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangzhou, Guangdong, China

  https://orcid.org/0009-0006-5493-5305

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• Yifei Li ,

  Contributed equally to this work with: Jiafang Li, Yifei Li

  Roles Investigation, Methodology, Validation, Writing – original draft

  Affiliations Department of Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangzhou, Guangdong, China

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• Siying Lin,

  Roles Methodology

  Affiliations Department of Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China, School of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, Guangdong, China

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• Jiahua Rao,

  Roles Methodology

  Affiliation School of Computer Science and Engineering, Sun Yat-sen University, Guangzhou, Guangdong, China

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• Huiying Zhao

  Roles Conceptualization, Writing – review & editing

  * E-mail: zhaohy8@mail.sysu.edu.cn

  Affiliations Department of Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangzhou, Guangdong, China

  https://orcid.org/0000-0001-9134-536X

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