-
Loading metrics
Open Access
Peer-reviewed
Research Article
Scaffold-Lab: Critical evaluation and ranking of protein backbone generation methods in a unified framework
-
Zhuoqi Zheng,
Roles Data curation, Investigation, Methodology, Resources, Validation, Writing – original draft
Affiliation State Key Laboratory of Microbial metabolism, Joint International Research Laboratory of Metabolic Developmental Sciences, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Shanghai, JiaoTong University, Shanghai, China
⨯ -
Bo Zhang,
Roles Data curation, Methodology
Affiliation State Key Laboratory of Microbial metabolism, Joint International Research Laboratory of Metabolic Developmental Sciences, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Shanghai, JiaoTong University, Shanghai, China
⨯ -
Bozitao Zhong,
Roles Methodology
Affiliation State Key Laboratory of Microbial metabolism, Joint International Research Laboratory of Metabolic Developmental Sciences, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Shanghai, JiaoTong University, Shanghai, China
⨯ -
Jinyu Yu,
Roles Methodology
Affiliation State Key Laboratory of Microbial metabolism, Joint International Research Laboratory of Metabolic Developmental Sciences, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Shanghai, JiaoTong University, Shanghai, China
⨯ -
Kexin Liu,
Roles Methodology
Affiliation State Key Laboratory of Microbial metabolism, Joint International Research Laboratory of Metabolic Developmental Sciences, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Shanghai, JiaoTong University, Shanghai, China
⨯ -
Zhengxin Li,
Roles Methodology
Affiliation State Key Laboratory of Microbial metabolism, Joint International Research Laboratory of Metabolic Developmental Sciences, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Shanghai, JiaoTong University, Shanghai, China
⨯ -
Junjie Zhu,
Roles Methodology
Affiliation State Key Laboratory of Microbial metabolism, Joint International Research Laboratory of Metabolic Developmental Sciences, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Shanghai, JiaoTong University, Shanghai, China
⨯ -
Ting Wei ,
Roles Investigation, Supervision
* E-mail: weitinging@sjtu.edu.cn (TW); haifengchen@sjtu.edu.cn (H-FC)
Affiliation State Key Laboratory of Microbial metabolism, Joint International Research Laboratory of Metabolic Developmental Sciences, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Shanghai, JiaoTong University, Shanghai, China
⨯ -
Hai-Feng Chen
Roles Conceptualization, Funding acquisition, Supervision
* E-mail: weitinging@sjtu.edu.cn (TW); haifengchen@sjtu.edu.cn (H-FC)
Affiliation State Key Laboratory of Microbial metabolism, Joint International Research Laboratory of Metabolic Developmental Sciences, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, School of Life Sciences and Biotechnology, Shanghai, JiaoTong University, Shanghai, China
⨯
Scaffold-Lab: Critical evaluation and ranking of protein backbone generation methods in a unified framework
- Zhuoqi Zheng,
- Bo Zhang,
- Bozitao Zhong,
- Jinyu Yu,
- Kexin Liu,
- Zhengxin Li,
- Junjie Zhu,
- Ting Wei,
- Hai-Feng Chen
- Published: May 22, 2026
- https://doi.org/10.1371/journal.pcbi.1014290