Time-dependent computational model of post-traumatic osteoarthritis to estimate how mechanoinflammatory mechanisms impact cartilage aggrecan content

• Atte S. A. Eskelinen ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: atte.eskelinen@uef.fi

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

  https://orcid.org/0000-0003-1516-3083

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• Joonas P. Kosonen,

  Roles Conceptualization, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

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• Moustafa Hamada,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

  https://orcid.org/0009-0006-4465-8631

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• Amir Esrafilian,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

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• Cristina Florea,

  Roles Conceptualization, Methodology, Supervision, Visualization, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

  https://orcid.org/0000-0001-7719-2600

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• Alan J. Grodzinsky,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Departments of Biological Engineering, Electrical Engineering and Computer Science, and Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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• Petri Tanska,

  Roles Conceptualization, Methodology, Supervision, Visualization, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

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• Rami K. Korhonen

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

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