HyperACP: A cutting-edge hybrid framework for anticancer peptide classification via scalable feature extraction and adaptive neighbor-based synthesis

Bangyi Zhang; Yun Zuo; Jun Wan; Jiayue Liu; Xiangrong Liu; Xiangxiang Zeng; Zhaohong Deng

doi:10.1371/journal.pcbi.1013489

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Open Access

Peer-reviewed

Research Article

HyperACP: A cutting-edge hybrid framework for anticancer peptide classification via scalable feature extraction and adaptive neighbor-based synthesis

Bangyi Zhang,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China
⨯
Yun Zuo ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: zuoyun@jiangnan.edu.cn

Affiliation School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China

https://orcid.org/0009-0003-4021-3836

⨯
Jun Wan,

Roles Formal analysis, Validation

Affiliation School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China
⨯
Jiayue Liu,

Roles Formal analysis, Validation

Affiliation School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China
⨯
Xiangrong Liu,

Roles Supervision, Writing – review & editing

Affiliation Department of Computer Science and Technology, National Institute for Data Science in Health and Medicine, Xiamen Key Laboratory of Intelligent Storage and Computing, Xiamen University, Xiamen, China
⨯
Xiangxiang Zeng,

Roles Supervision, Writing – review & editing

Affiliation School of Information Science and Engineering, Hunan University, Yuelu, Changsha, China
⨯
Zhaohong Deng

Roles Supervision, Writing – review & editing

Affiliation School of Artificial Intelligence and Computer Science, Jiangnan University, Wuxi, China
⨯

HyperACP: A cutting-edge hybrid framework for anticancer peptide classification via scalable feature extraction and adaptive neighbor-based synthesis

Bangyi Zhang,
Yun Zuo,
Jun Wan,
Jiayue Liu,
Xiangrong Liu,
Xiangxiang Zeng,
Zhaohong Deng

Published: September 11, 2025
https://doi.org/10.1371/journal.pcbi.1013489

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