Mathematical modeling suggests 14-3-3 proteins modulate RAF paradoxical activation

• Gaurav Mendiratta,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America

  https://orcid.org/0000-0001-5091-348X

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• Kodye Abbott,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America

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• Yao-Cheng Li,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America

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• Jingting Yu,

  Roles Data curation, Formal analysis, Software, Writing – review & editing

  Affiliation The Razavi Newman Integrative Genomics and Bioinformatics Core (IGC), Salk Institute for Biological Studies, La Jolla, California, United States of America

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• Peter Carlip,

  Roles Validation, Writing – review & editing

  Affiliation Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America

  https://orcid.org/0009-0003-8257-2001

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• Melinda Tong,

  Roles Validation, Writing – review & editing

  Affiliation Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America

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• Jianfeng Huang,

  Roles Methodology, Validation

  Affiliation Integrative Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America

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• Maxim N. Shokhirev,

  Roles Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliation The Razavi Newman Integrative Genomics and Bioinformatics Core (IGC), Salk Institute for Biological Studies, La Jolla, California, United States of America

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• Thomas McFall,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Biochemistry and MCW Cancer Center, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America

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• Geoffrey M. Wahl,

  Roles Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States of America

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• Edward C. Stites

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: edward.stites@yale.edu

  Affiliations Department of Laboratory Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America, Yale Cancer Center, Yale School of Medicine, New Haven, Connecticut, United States of America

  https://orcid.org/0000-0002-3783-7336

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