MMP release following cartilage injury leads to collagen loss in intact tissue: A computational study

• Moustafa Hamada ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: moustafa.hamada@uef.fi

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

  https://orcid.org/0009-0006-4465-8631

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• Atte S. A. Eskelinen,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Visualization, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

  https://orcid.org/0000-0003-1516-3083

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• Joonas P. Kosonen,

  Roles Conceptualization, Methodology, Visualization, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

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• Cristina Florea,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

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• Alan J. Grodzinsky,

  Roles Conceptualization, Methodology, Resources, Writing – review & editing

  Affiliation Departments of Biological Engineering, Electrical Engineering and Computer Science, and Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United Stated of America

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• Petri Tanska,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Technical Physics, University of Eastern Finland, Kuopio, Finland, Department of Oncology, Kuopio University Hospital, Wellbeing Services County of North Savo, Kuopio, Finland

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• Rami K. Korhonen

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Technical Physics, University of Eastern Finland, Kuopio, Finland

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