Digital twin for sex-specific identification of class III antiarrhythmic drugs based on in vitro measurements, computer models, and machine learning tools

• Jieyun Bai ,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jbai996@aucklanduni.ac.nz (JB); speciahual@icloud.com (HL)

  Affiliations Department of Cardiovascular Surgery, The first Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China, Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand

  https://orcid.org/0000-0002-2847-350X

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• Weishan Wang,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Cardiovascular Surgery, The first Affiliated Hospital of Jinan University, Jinan University, Guangzhou, China

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• Xiaoshen Zhang,

  Roles Investigation, Project administration, Resources, Writing – original draft, Writing – review & editing

  Affiliation The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, Guangzhou, China

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• Hua Lu ,

  Roles Conceptualization, Investigation, Supervision, Validation, Writing – review & editing

  * E-mail: jbai996@aucklanduni.ac.nz (JB); speciahual@icloud.com (HL)

  Affiliation The First Affiliated Hospital of Jinan University, Jinan University, Guangzhou, Guangzhou, China

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• Henggui Zhang,

  Roles Formal analysis, Methodology, Validation, Writing – review & editing

  Affiliation Biological Physics Group, Department of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom

  https://orcid.org/0000-0002-0863-5807

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• Alexander V. Panfilov,

  Roles Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliations Department of Physics and Astronomy, Ghent University, Gent, Belgium, World-Class Research Center “Digital biodesign and personalized healthcare”, I.M. Sechenov First Moscow State Medical University, Moscow, Russia

  https://orcid.org/0000-0003-2643-642X

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• Jichao Zhao

  Roles Formal analysis, Investigation, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand

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