Multimodal CustOmics: A unified and interpretable multi-task deep learning framework for multimodal integrative data analysis in oncology

• Hakim Benkirane,

  Roles Conceptualization, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Université Paris-Saclay, CentraleSupélec, Laboratory of Mathematics and Computer Science (MICS), Gif-sur-Yvette, France, IHU PRISM, National PRecISion Medicine Center in Oncology, Gustave Roussy, Villejuif, France, Inserm U1018 Oncostat, Équipe Labellisée Ligue Contre le Cancer, Université Paris-Saclay, Villejuif, France, Université Paris-Saclay, Faculty of Medicine, Le Kremlin Bicêtre, France

  https://orcid.org/0000-0002-1039-3878

  ⨯
• Maria Vakalopoulou,

  Roles Supervision, Writing – original draft

  Affiliations Université Paris-Saclay, CentraleSupélec, Laboratory of Mathematics and Computer Science (MICS), Gif-sur-Yvette, France, IHU PRISM, National PRecISion Medicine Center in Oncology, Gustave Roussy, Villejuif, France

  ⨯
• David Planchard,

  Roles Data curation

  Affiliations Université Paris-Saclay, Faculty of Medicine, Le Kremlin Bicêtre, France, Department of Medical Oncology, Thoracic Group and International Center for Thoracic Cancers (CICT), Gustave Roussy, Université Paris-Saclay, Villejuif, France

  ⨯
• Julien Adam,

  Roles Data curation

  Affiliations Université Paris-Saclay, Faculty of Medicine, Le Kremlin Bicêtre, France, Inserm U1186, Gustave Roussy, Université Paris-Saclay, Villejuif, France

  ⨯
• Ken Olaussen,

  Roles Validation, Data curation

  Affiliations Université Paris-Saclay, Faculty of Medicine, Le Kremlin Bicêtre, France, Inserm U981, Gustave Roussy, Université Paris-Saclay, Villejuif, France

  ⨯
• Stefan Michiels ,

  Contributed equally to this work with: Stefan Michiels, Paul-Henry Cournède

  Roles Validation, Supervision, Funding acquisition, Writing – original draft, Writing – review & editing

  Affiliations Inserm U1018 Oncostat, Équipe Labellisée Ligue Contre le Cancer, Université Paris-Saclay, Villejuif, France, Bureau de Biostatistique et d’Épidémiologie, Gustave Roussy, Université Paris-Saclay, Villejuif, France

  ⨯
• Paul-Henry Cournède

  Contributed equally to this work with: Stefan Michiels, Paul-Henry Cournède

  Roles Validation, Supervision, Funding acquisition, Resources, Writing – original draft, Writing – review & editing

  * E-mail: paul-henry.cournede@centralesupelec.fr

  Affiliations Université Paris-Saclay, CentraleSupélec, Laboratory of Mathematics and Computer Science (MICS), Gif-sur-Yvette, France, IHU PRISM, National PRecISion Medicine Center in Oncology, Gustave Roussy, Villejuif, France

  https://orcid.org/0000-0001-7679-6197

  ⨯