Quantifying expression and metabolic activity of genes regulated by pregnane X receptor in primary human hepatocyte spheroids

• Lukáš Lochman,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

  https://orcid.org/0000-0001-8501-2868

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• Ellen Tanaka Kahiya ,

  Contributed equally to this work with: Ellen Tanaka Kahiya, Bechara Saade

  Roles Writing – original draft, Writing – review & editing

  * E-mail: bernhauve@faf.cuni.cz

  Affiliation Department of Biophysics and Physical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

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• Bechara Saade ,

  Contributed equally to this work with: Ellen Tanaka Kahiya, Bechara Saade

  Roles Writing – original draft, Writing – review & editing

  * E-mail: bernhauve@faf.cuni.cz

  Affiliation Department of Biophysics and Physical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

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• Tomáš Smutný,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

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• Jurjen Duintjer Tebbens,

  Roles Writing – original draft, Writing – review & editing

  Affiliations Department of Biophysics and Physical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic, Department of Artificial Intelligence, Institute of Computer Science of the Czech Academy of Sciences, Prague, Czech Republic

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• Petr Pávek,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

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• Veronika Bernhauerová

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: bernhauve@faf.cuni.cz

  Affiliation Department of Biophysics and Physical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, Hradec Králové, Czech Republic

  https://orcid.org/0000-0002-5595-4579

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