Mechanistic modeling suggests stroma-targeting antibody-drug conjugates as an alternative to cancer-targeting in cases of heterogeneous target exspression

• N. Ezgi Wood ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: nihal.wood@bms.com

  Affiliation Quantitative Systems Pharmacology, Bristol Myers Squibb, Princeton, New Jersey, United States of America

  https://orcid.org/0000-0002-1874-9226

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• Anıl Cengiz,

  Roles Formal analysis, Investigation, Software, Writing – review & editing

  Affiliation Department of Mathematics, University of Utah, Salt Lake City, Utah, United States of America

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• Ming Gao,

  Roles Software, Writing – review & editing

  Affiliation Quantitative Systems Pharmacology, Bristol Myers Squibb, Cambridge, Massachusetts, United States of America

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• Alexander V. Ratushny,

  Roles Conceptualization, Writing – review & editing

  Affiliation Quantitative Systems Pharmacology, Bristol Myers Squibb, Seattle, Washington, United States of America

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• Ronny Straube

  Roles Methodology, Software

  Affiliation Quantitative Systems Pharmacology, Bristol Myers Squibb, Princeton, New Jersey, United States of America

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