Multiscale modelling shows how cell-ECM interactions impact ECM fibre alignment and cell detachment

• Juan Arellano-Tintó ,

  Roles Conceptualization, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  * E-mail: jarellano@crm.cat

  Affiliations Centre de Recerca Matemàtica, Bellaterra (Barcelona), Spain, Departament de Matemàtiques, Universitat Autònoma de Barcelona, Bellaterra (Barcelona), Spain

  https://orcid.org/0009-0002-9183-3229

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• Daria Stepanova,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Centre de Recerca Matemàtica, Bellaterra (Barcelona), Spain

  https://orcid.org/0000-0003-1771-1987

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• Helen M. Byrne,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliations Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom, Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

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• Philip K. Maini,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom

  https://orcid.org/0000-0002-0146-9164

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• Tomás Alarcón

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliations Centre de Recerca Matemàtica, Bellaterra (Barcelona), Spain, Departament de Matemàtiques, Universitat Autònoma de Barcelona, Bellaterra (Barcelona), Spain, Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain, Barcelona Collaboratorium for Theoretical and Predictive Biology, Barcelona, Spain

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