Beyond IC₅₀—A computational dynamic model of drug resistance in enzyme inhibition treatment

• J. Roadnight Sheehan,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Mechanical and Industrial Engineering, Norwegian University of Science and Technology, Trondheim, Norway

  https://orcid.org/0000-0001-7169-6226

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• Astrid S. de Wijn ,

  Roles Conceptualization, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: astrid.dewijn@ntnu.no

  Affiliation Department of Mechanical and Industrial Engineering, Norwegian University of Science and Technology, Trondheim, Norway

  https://orcid.org/0000-0003-4664-6811

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• Thales Souza Freire,

  Roles Formal analysis, Investigation, Methodology

  Affiliation Institute of Physics of the University of São Paulo, Department of General Physics, São Paulo, Brazil

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• Ran Friedman

  Roles Conceptualization, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Department of Chemistry and Biomedical Sciences, Linnaeus University, Kalmar, Sweden

  https://orcid.org/0000-0001-8696-3104

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