Integrative pan-cancer analysis reveals a common architecture of dysregulated transcriptional networks characterized by loss of enhancer methylation

• Jørgen Ankill,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Cancer Genetics, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

  https://orcid.org/0000-0002-5752-0299

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• Zhi Zhao,

  Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Cancer Genetics, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway, Oslo Centre for Biostatistics and Epidemiology (OCBE), Faculty of Medicine, University of Oslo, Oslo, Norway

  https://orcid.org/0000-0003-2325-1438

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• Xavier Tekpli,

  Roles Investigation, Resources, Writing – original draft, Writing – review & editing

  Affiliation Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

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• Elin H. Kure,

  Roles Investigation, Resources, Writing – original draft, Writing – review & editing

  Affiliation Department of Cancer Genetics, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway

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• Vessela N. Kristensen,

  Roles Investigation, Writing – original draft, Writing – review & editing

  Affiliations Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway, Department of Medical Genetics, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway

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• Anthony Mathelier,

  Roles Investigation, Resources, Writing – original draft, Writing – review & editing

  Affiliations Department of Medical Genetics, Institute of Clinical Medicine, University of Oslo and Oslo University Hospital, Oslo, Norway, Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, University of Norway, Oslo, Norway, Department of Pharmacy, University of Oslo, Oslo, Norway

  https://orcid.org/0000-0001-5127-5459

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• Thomas Fleischer

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: thomas.fleischer@rr-research.no

  Affiliation Department of Cancer Genetics, Institute of Cancer Research, Oslo University Hospital, Oslo, Norway

  https://orcid.org/0000-0003-0985-8460

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