Database size positively correlates with the loss of species-level taxonomic resolution for the 16S rRNA and other prokaryotic marker genes

• Seth Commichaux ,

  Contributed equally to this work with: Seth Commichaux, Tu Luan, Harihara Subrahmaniam Muralidharan, Mihai Pop

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Seth.Commichaux@fda.hhs.gov

  Affiliation Center for Food Safety and Nutrition, Food and Drug Administration, Laurel, Maryland, United States of America

  https://orcid.org/0000-0002-2162-4205

  ⨯
• Tu Luan ,

  Contributed equally to this work with: Seth Commichaux, Tu Luan, Harihara Subrahmaniam Muralidharan, Mihai Pop

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Computer Science, University of Maryland, College Park, Maryland, United States of America, Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

  ⨯
• Harihara Subrahmaniam Muralidharan ,

  Contributed equally to this work with: Seth Commichaux, Tu Luan, Harihara Subrahmaniam Muralidharan, Mihai Pop

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Computer Science, University of Maryland, College Park, Maryland, United States of America, Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

  ⨯
• Mihai Pop

  Contributed equally to this work with: Seth Commichaux, Tu Luan, Harihara Subrahmaniam Muralidharan, Mihai Pop

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Computer Science, University of Maryland, College Park, Maryland, United States of America, Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

  https://orcid.org/0000-0001-9617-5304

  ⨯