Molecular dynamics simulations reveal how vinculin refolds partially unfolded talin rod helices to stabilize them against mechanical force

• Vasyl V. Mykuliak ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: vasyl.mykuliak@tuni.fi (VVM); vesa.hytonen@tuni.fi (VPH)

  Affiliation Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland

  https://orcid.org/0000-0002-2522-9907

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• Rolle Rahikainen ,

  Contributed equally to this work with: Rolle Rahikainen, Neil J. Ball

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland

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• Neil J. Ball ,

  Contributed equally to this work with: Rolle Rahikainen, Neil J. Ball

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Current address: Department of Biochemistry, Cell & Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom

  Affiliation School of Biosciences, University of Kent, Canterbury, United Kingdom

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• Giovanni Bussi,

  Roles Methodology

  Affiliation Scuola Internazionale Superiore di Studi Avanzati, SISSA, Trieste, Italy

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• Benjamin T. Goult,

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  Current address: Department of Biochemistry, Cell & Systems Biology, Institute of Systems, Molecular & Integrative Biology, University of Liverpool, Liverpool, United Kingdom

  Affiliation School of Biosciences, University of Kent, Canterbury, United Kingdom

  https://orcid.org/0000-0002-3438-2807

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• Vesa P. Hytönen

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: vasyl.mykuliak@tuni.fi (VVM); vesa.hytonen@tuni.fi (VPH)

  Affiliations Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland, Fimlab Laboratories, Tampere, Finland

  https://orcid.org/0000-0002-9357-1480

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