GeneCOCOA: Detecting context-specific functions of individual genes using co-expression data

Simonida Zehr; Sebastian Wolf; Thomas Oellerich; Matthias S Leisegang; Ralf P Brandes; Marcel H Schulz; Timothy Warwick

doi:10.1371/journal.pcbi.1012278

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Peer-reviewed

GeneCOCOA: Detecting context-specific functions of individual genes using co-expression data

Simonida Zehr,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Goethe University Frankfurt, Institute for Cardiovascular Physiology, Frankfurt am Main, Germany, German Centre for Cardiovascular Research (DZHK), Partner site Rhine-Main, Frankfurt am Main, Germany
⨯
Sebastian Wolf,

Roles Methodology, Resources

Affiliation Goethe University Frankfurt, University Hospital, Department of Medicine II, Haematology/Oncology, Frankfurt am Main, Germany
⨯
Thomas Oellerich,

Roles Resources

Affiliation Goethe University Frankfurt, University Hospital, Department of Medicine II, Haematology/Oncology, Frankfurt am Main, Germany
⨯
Matthias S Leisegang,

Roles Resources, Writing – review & editing

Affiliations Goethe University Frankfurt, Institute for Cardiovascular Physiology, Frankfurt am Main, Germany, German Centre for Cardiovascular Research (DZHK), Partner site Rhine-Main, Frankfurt am Main, Germany

https://orcid.org/0000-0002-6084-6484

⨯
Ralf P Brandes,

Roles Resources, Supervision, Writing – review & editing

Affiliations Goethe University Frankfurt, Institute for Cardiovascular Physiology, Frankfurt am Main, Germany, German Centre for Cardiovascular Research (DZHK), Partner site Rhine-Main, Frankfurt am Main, Germany
⨯
Marcel H Schulz,

Roles Conceptualization, Software, Supervision, Writing – original draft, Writing – review & editing

Affiliations German Centre for Cardiovascular Research (DZHK), Partner site Rhine-Main, Frankfurt am Main, Germany, Goethe University Frankfurt, Institute for Computational Genomic Medicine, Frankfurt am Main, Germany
⨯
Timothy Warwick

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: warwick@vrc.uni-frankfurt.de

Affiliations Goethe University Frankfurt, Institute for Cardiovascular Physiology, Frankfurt am Main, Germany, German Centre for Cardiovascular Research (DZHK), Partner site Rhine-Main, Frankfurt am Main, Germany

https://orcid.org/0000-0002-6804-2931

⨯

GeneCOCOA: Detecting context-specific functions of individual genes using co-expression data

Simonida Zehr,
Sebastian Wolf,
Thomas Oellerich,
Matthias S Leisegang,
Ralf P Brandes,
Marcel H Schulz,
Timothy Warwick

Published: March 31, 2025
https://doi.org/10.1371/journal.pcbi.1012278

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