Machine learning on multiple epigenetic features reveals H3K27Ac as a driver of gene expression prediction across patients with glioblastoma

• Yusuke Suita ,

  Contributed equally to this work with: Yusuke Suita, Hardy Bright Jr

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Laboratory of Cancer Epigenetics and Plasticity, Department of Neurosurgery, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0002-8387-4162

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• Hardy Bright Jr ,

  Contributed equally to this work with: Yusuke Suita, Hardy Bright Jr

  Roles Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Data Science Institute, Brown University, Providence, Rhode Island, United States of America

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• Yuan Pu,

  Roles Formal analysis, Investigation

  Affiliation Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0009-0008-4227-1833

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• Merih Deniz Toruner,

  Roles Formal analysis, Investigation

  Affiliations Laboratory of Cancer Epigenetics and Plasticity, Department of Neurosurgery, Brown University, Providence, Rhode Island, United States of America, Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0001-7447-8654

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• Jordan Idehen,

  Roles Formal analysis, Investigation

  Affiliation Department of Computer Science, Brown University, Providence, Rhode Island, United States of America

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• Nikos Tapinos ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: nikos_tapinos@brown.edu (NT); ritambhara@brown.edu (RS)

  Affiliations Laboratory of Cancer Epigenetics and Plasticity, Department of Neurosurgery, Brown University, Providence, Rhode Island, United States of America, Brown RNA Center, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0002-3798-5363

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• Ritambhara Singh

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: nikos_tapinos@brown.edu (NT); ritambhara@brown.edu (RS)

  Affiliations Center for Computational Molecular Biology, Brown University, Providence, Rhode Island, United States of America, Department of Computer Science, Brown University, Providence, Rhode Island, United States of America

  https://orcid.org/0000-0002-7523-160X

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