ST-CellSeg: Cell segmentation for imaging-based spatial transcriptomics using multi-scale manifold learning

• Youcheng Li ,

  Contributed equally to this work with: Youcheng Li, Leann Lac

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Biochemistry, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada, Department of Computer Science, Western University, London, Ontario, Canada, Department of Computer Science, University of Manitoba, Winnipeg, Manitoba, Canada

  ⨯
• Leann Lac ,

  Contributed equally to this work with: Youcheng Li, Leann Lac

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Department of Computer Science, University of Manitoba, Winnipeg, Manitoba, Canada, Department of Statistics, University of Manitoba, Winnipeg, Manitoba, Canada

  ⨯
• Qian Liu,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Applied Computer Science, University of Winnipeg, Winnipeg, Manitoba, Canada

  ⨯
• Pingzhao Hu

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: phu49@uwo.ca

  Affiliations Department of Biochemistry, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada, Department of Computer Science, Western University, London, Ontario, Canada, Department of Computer Science, University of Manitoba, Winnipeg, Manitoba, Canada, Department of Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada, Department of Oncology, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada, The Children’s Health Research Institute, Lawson Health Research Institute, London, Ontario, Canada

  https://orcid.org/0000-0002-9546-2245

  ⨯