Physiology-informed regularisation enables training of universal differential equation systems for biological applications

• Max de Rooij ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft

  * E-mail: m.d.rooij@tue.nl

  Affiliations Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, Eindhoven Artificial Intelligence Systems Institute (EAISI), Eindhoven University of Technology, Eindhoven, Netherlands

  https://orcid.org/0009-0006-1298-7385

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• Balázs Erdős,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Data Science and Knowledge Discovery, Simula Metropolitan Center for Digital Engineering, Oslo, Norway

  https://orcid.org/0000-0001-8643-4915

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• Natal A. W. van Riel,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, Eindhoven Artificial Intelligence Systems Institute (EAISI), Eindhoven University of Technology, Eindhoven, Netherlands, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, Netherlands

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• Shauna D. O’Donovan

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, Eindhoven Artificial Intelligence Systems Institute (EAISI), Eindhoven University of Technology, Eindhoven, Netherlands

  https://orcid.org/0000-0003-2253-4903

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