Mechanistic computational modeling of monospecific and bispecific antibodies targeting interleukin-6/8 receptors

• Christina M. P. Ray ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: christyray@jhmi.edu

  Affiliations Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Medical-Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0001-7552-9759

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• Huilin Yang,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliations Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America, Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0002-1193-2087

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• Jamie B. Spangler,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America, Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America, Bloomberg Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University, Baltimore, Maryland, United States of America, Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0001-8187-3732

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• Feilim Mac Gabhann

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America, Institute for Nano Biotechnology (INBT), Johns Hopkins University, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0003-3481-7740

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