Combined multiplex panel test results are a poor estimate of disease prevalence without adjustment for test error

• Robert Challen ,

  Roles Conceptualization, Formal analysis, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rob.challen@bristol.ac.uk

  Affiliations Bristol Vaccine Centre, Schools of Population Health Sciences and of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom, Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom

  https://orcid.org/0000-0002-5504-7768

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• Anastasia Chatzilena,

  Roles Validation, Writing – review & editing

  Affiliations Bristol Vaccine Centre, Schools of Population Health Sciences and of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom, Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom

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• George Qian,

  Roles Writing – review & editing

  Affiliations Bristol Vaccine Centre, Schools of Population Health Sciences and of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom, Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom

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• Glenda Oben,

  Roles Writing – review & editing

  Affiliations Bristol Vaccine Centre, Schools of Population Health Sciences and of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom, Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom

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• Rachel Kwiatkowska,

  Roles Writing – review & editing

  Affiliations Population Health Sciences, University of Bristol, United Kingdom, NIHR Health Protection Unit in Behavioural Science and Evaluation, University of Bristol, United Kingdom

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• Catherine Hyams,

  Roles Writing – review & editing

  Affiliation Bristol Vaccine Centre, Schools of Population Health Sciences and of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom

  https://orcid.org/0000-0003-3923-1773

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• Adam Finn,

  Roles Supervision, Writing – review & editing

  Affiliation Bristol Vaccine Centre, Schools of Population Health Sciences and of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom

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• Krasimira Tsaneva-Atanasova,

  Roles Supervision, Validation, Writing – review & editing

  Affiliation Department of Mathematics and Statistics, University of Exeter, United Kingdom

  https://orcid.org/0000-0002-6294-7051

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• Leon Danon

  Roles Conceptualization, Formal analysis, Supervision, Validation, Writing – review & editing

  Affiliations Bristol Vaccine Centre, Schools of Population Health Sciences and of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom, Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom

  https://orcid.org/0000-0002-7076-1871

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