Spatial transcriptome-guided multi-scale framework connects P. aeruginosa metabolic states to oxidative stress biofilm microenvironment

• Tracy J. Kuper,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia, United States of America

  https://orcid.org/0000-0003-2491-1557

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• Mohammad Mazharul Islam,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America

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• Shayn M. Peirce-Cottler,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America

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• Jason A. Papin,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America

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• Roseanne M Ford

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: rmf3f@virginia.edu

  Affiliation Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia, United States of America

  https://orcid.org/0000-0001-6763-3927

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