Mathematical model of oxygen, nutrient, and drug transport in tuberculosis granulomas

• Meenal Datta ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: mdatta@nd.edu (MD); rjain@mgh.harvard.edu (RKJ)

  Affiliations Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana, United States of America

  https://orcid.org/0000-0001-5727-8992

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• McCarthy Kennedy,

  Roles Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – review & editing

  Affiliation Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana, United States of America

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• Saeed Siri,

  Roles Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – review & editing

  Affiliation Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, Indiana, United States of America

  https://orcid.org/0000-0002-4185-0680

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• Laura E. Via,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease (NIAID), National Institutes of Health, Bethesda, Maryland, United States of America

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• James W. Baish,

  Roles Conceptualization, Methodology, Resources, Writing – review & editing

  Affiliation Department of Biomedical Engineering, Bucknell University, Lewisburg, Pennsylvania, United States of America

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• Lei Xu,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Véronique Dartois,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Center for Discovery and Innovation, Hackensack Meridian School of Medicine, Hackensack Meridian Health, Nutley, New Jersey, United States of America

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• Clifton E. Barry 3rd,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease (NIAID), National Institutes of Health, Bethesda, Maryland, United States of America

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• Rakesh K. Jain

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: mdatta@nd.edu (MD); rjain@mgh.harvard.edu (RKJ)

  Affiliation Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0001-7571-3548

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