DepoScope: Accurate phage depolymerase annotation and domain delineation using large language models

Robby Concha-Eloko; Michiel Stock; Bernard De Baets; Yves Briers; Rafael Sanjuán; Pilar Domingo-Calap; Dimitri Boeckaerts

doi:10.1371/journal.pcbi.1011831

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Peer-reviewed

DepoScope: Accurate phage depolymerase annotation and domain delineation using large language models

Robby Concha-Eloko,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Paterna, Spain
⨯
Michiel Stock,

Roles Supervision, Writing – review & editing

Affiliation KERMIT, Department of Data Analysis and Mathematical Modelling, Ghent University, Ghent, Belgium
⨯
Bernard De Baets,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation KERMIT, Department of Data Analysis and Mathematical Modelling, Ghent University, Ghent, Belgium

https://orcid.org/0000-0002-3876-620X

⨯
Yves Briers,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation Laboratory of Applied Biotechnology, Department of Biotechnology, Ghent University, Ghent, Belgium
⨯
Rafael Sanjuán,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Paterna, Spain
⨯
Pilar Domingo-Calap,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliation Institute for Integrative Systems Biology (I2SysBio), Universitat de Valencia-CSIC, Paterna, Spain
⨯
Dimitri Boeckaerts

Roles Conceptualization, Formal analysis, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: dimi.boeckaerts@gmail.com

Affiliations KERMIT, Department of Data Analysis and Mathematical Modelling, Ghent University, Ghent, Belgium, Laboratory of Applied Biotechnology, Department of Biotechnology, Ghent University, Ghent, Belgium

https://orcid.org/0000-0002-7668-2840

⨯

DepoScope: Accurate phage depolymerase annotation and domain delineation using large language models

Robby Concha-Eloko,
Michiel Stock,
Bernard De Baets,
Yves Briers,
Rafael Sanjuán,
Pilar Domingo-Calap,
Dimitri Boeckaerts

Published: August 5, 2024
https://doi.org/10.1371/journal.pcbi.1011831

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Protein domains
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