Regulus infers signed regulatory relations from few samples’ information using discretization and likelihood constraints

• Marine Louarn,

  Roles Conceptualization, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Current address: Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada

  Affiliations Univ Rennes, CNRS, Inria, IRISA - UMR 6074, Rennes, France, UMR_S 1236, Université Rennes 1, INSERM, Etablissement Français du Sang, Rennes, France

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• Guillaume Collet,

  Roles Software

  Affiliation Univ Rennes, CNRS, Inria, IRISA - UMR 6074, Rennes, France

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• Ève Barré,

  Roles Methodology, Software

  Affiliation Univ Rennes, CNRS, Inria, IRISA - UMR 6074, Rennes, France

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• Thierry Fest,

  Roles Funding acquisition, Supervision

  Affiliations UMR_S 1236, Université Rennes 1, INSERM, Etablissement Français du Sang, Rennes, France, Laboratoire d’Hématologie, Pôle de Biologie, CHU de Rennes, Rennes, France

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• Olivier Dameron,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Univ Rennes, CNRS, Inria, IRISA - UMR 6074, Rennes, France

  https://orcid.org/0000-0001-8959-7189

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• Anne Siegel,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Univ Rennes, CNRS, Inria, IRISA - UMR 6074, Rennes, France

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• Fabrice Chatonnet

  Roles Conceptualization, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: fabrice.chatonnet@ens-lyon.org

  Current address: U1111 CIRI, Lymphoma ImmunoBiology team, INSERM, Université de Lyon, Oullins, France

  Affiliations UMR_S 1236, Université Rennes 1, INSERM, Etablissement Français du Sang, Rennes, France, Laboratoire d’Hématologie, Pôle de Biologie, CHU de Rennes, Rennes, France

  https://orcid.org/0000-0003-3639-6775

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