Mechanistic multiscale modelling of energy metabolism in human astrocytes reveals the impact of morphology changes in Alzheimer’s Disease

• Sofia Farina,

  Roles Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Engineering, University of Luxembourg, Esch-sur-Alzette, Luxembourg

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• Valérie Voorsluijs,

  Roles Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliations LCSB-Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg, Department of Physics and Material Science, University of Luxembourg, Luxembourg, Luxembourg

  https://orcid.org/0000-0003-2551-0632

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• Sonja Fixemer,

  Roles Data curation, Writing – review & editing

  Affiliations LCSB-Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg, Luxembourg Center of Neuropathology (LCNP), Dudelange, Luxembourg

  https://orcid.org/0000-0002-2312-6947

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• David S. Bouvier,

  Roles Supervision, Writing – review & editing

  Affiliations LCSB-Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg, Luxembourg Center of Neuropathology (LCNP), Dudelange, Luxembourg, Laboratoire national de santé (LNS), National Center of Pathology (NCP), Dudelange, Luxembourg

  https://orcid.org/0000-0002-8630-1044

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• Susanne Claus,

  Roles Methodology, Writing – review & editing

  Affiliation Onera, Palaiseau, France

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• Mark H. Ellisman,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Neurosciences, University of California San Diego, California, United States of America

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• Stéphane P. A. Bordas ,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  * E-mail: stephane.bordas@alum.northwestern.edu (SPAB); alexander.skupin@uni.lu (AS)

  Affiliation Department of Engineering, University of Luxembourg, Esch-sur-Alzette, Luxembourg

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• Alexander Skupin

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: stephane.bordas@alum.northwestern.edu (SPAB); alexander.skupin@uni.lu (AS)

  Affiliations LCSB-Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg, Department of Physics and Material Science, University of Luxembourg, Luxembourg, Luxembourg, Department of Neurosciences, University of California San Diego, California, United States of America

  https://orcid.org/0000-0002-8955-8304

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