In-silico and in-vitro morphometric analysis of intestinal organoids

Sandra Montes-Olivas; Danny Legge; Abbie Lund; Alexander G. Fletcher; Ann C. Williams; Lucia Marucci; Martin Homer

doi:10.1371/journal.pcbi.1011386

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Open Access

Peer-reviewed

Research Article

In-silico and in-vitro morphometric analysis of intestinal organoids

Sandra Montes-Olivas,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliation Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom

https://orcid.org/0000-0002-7415-3558

⨯
Danny Legge,

Roles Data curation, Resources

Affiliation Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, United Kingdom

https://orcid.org/0000-0002-3897-5861

⨯
Abbie Lund,

Roles Data curation, Software

Affiliation Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom
⨯
Alexander G. Fletcher,

Roles Methodology, Software, Writing – review & editing

Affiliations School of Mathematics and Statistics, University of Sheffield, Sheffield, United Kingdom, Bateson Centre, University of Sheffield, Sheffield, United Kingdom
⨯
Ann C. Williams,

Roles Data curation, Methodology, Resources, Writing – review & editing

Affiliation Colorectal Tumour Biology Group, School of Cellular and Molecular Medicine, Faculty of Life Sciences, University of Bristol, Bristol, United Kingdom

https://orcid.org/0000-0002-6009-7137

⨯
Lucia Marucci ,

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: lucia.marucci@bristol.ac.uk (LM); martin.homer@bristol.ac.uk (MH)

¶‡ These authors are joint senior authors on this work.

Affiliations Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom, School of Cellular and Molecular Medicine, University of Bristol, Bristol, United Kingdom, BrisSynBio, Bristol, United Kingdom

https://orcid.org/0000-0002-7553-6358

⨯
Martin Homer

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

* E-mail: lucia.marucci@bristol.ac.uk (LM); martin.homer@bristol.ac.uk (MH)

¶‡ These authors are joint senior authors on this work.

Affiliation Department of Engineering Mathematics, University of Bristol, Bristol, United Kingdom

https://orcid.org/0000-0002-9848-1409

⨯

In-silico and in-vitro morphometric analysis of intestinal organoids

Sandra Montes-Olivas,
Danny Legge,
Abbie Lund,
Alexander G. Fletcher,
Ann C. Williams,
Lucia Marucci,
Martin Homer

Published: August 14, 2023
https://doi.org/10.1371/journal.pcbi.1011386

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