Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators

• Marina Strocchi ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Visualization, Writing – original draft

  * E-mail: marina.strocchi@kcl.ac.uk

  Affiliations School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, National Heart and Lung Institute, Imperial College London, London, United Kingdom

  https://orcid.org/0000-0003-1312-251X

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• Stefano Longobardi,

  Roles Software, Writing – review & editing

  Affiliation School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom

  https://orcid.org/0000-0002-0111-0047

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• Christoph M. Augustin,

  Roles Software, Writing – review & editing

  Affiliations Medical University of Graz, Graz, Austria, BioTechMed-Graz, Graz, Austria

  https://orcid.org/0000-0001-6341-4014

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• Matthias A. F. Gsell,

  Roles Software, Writing – review & editing

  Affiliation Medical University of Graz, Graz, Austria

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• Argyrios Petras,

  Roles Software, Writing – review & editing

  Affiliation Johann Radon Institute for Computational and Applied Mathematics (RICAM), Linz, Austria

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• Christopher A. Rinaldi,

  Roles Data curation, Writing – review & editing

  Affiliations School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom

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• Edward J. Vigmond,

  Roles Software, Writing – review & editing

  Affiliations University of Bordeaux, CNRS, Bordeaux, Talence, France, IHU Liryc, Bordeaux, Talence, France

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• Gernot Plank,

  Roles Software, Writing – review & editing

  Affiliations Medical University of Graz, Graz, Austria, BioTechMed-Graz, Graz, Austria

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• Chris J. Oates,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Newcastle University, Newcastle upon Tyne, United Kingdom

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• Richard D. Wilkinson,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation University of Nottingham, Nottingham, United Kingdom

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• Steven A. Niederer

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliations School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, National Heart and Lung Institute, Imperial College London, London, United Kingdom, Alan Turing Institute, London, United Kingdom

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